San Antonio, Florida
San Antonio's commercial ground moved when the road did. The new SR 52 alignment opened in February 2023, south of town, linking I-75 and US 301. The old route through town carries County Road 52. FDOT started interchange improvements at I-75 and SR 52 in April 2026, and two master-planned projects sit near the interchange.
The pipeline here is large. It isn't absorbed. Both facts matter, and which one matters more depends on what you own or what you're trying to buy.
I work commercial property in San Antonio and northeast Pasco County. The work starts with what you need the property to do, then tests it against zoning, access, utilities, timing, and what the market is actually taking down.
By the Numbers
University of Florida BEBR; REBusinessOnline. Census does not publish QuickFacts estimates for places under 5,000. Pulled October 2, 2026. Full data tables →
On the Ground
A 965-acre mixed-use development at I-75 and SR 52 by Columnar. Its 75 Logistics industrial park is entitled up to 4.5 million SF; the first phase of three rear-load buildings, more than 480,000 SF, was reported under construction in November 2024. Later phases plan office, about 3,500 residential units, retail, and two hotels.
About 330 acres at SR 52 and McKendree Road, acquired November 7, 2023. Entitled for 1.2 million SF of industrial, 400,000 SF of retail, 400,000 SF of office and commercial, and 1,000 apartments. The developer partner reports signed LOIs or leases with Walmart and others. No opening dates are confirmed.
A Target fulfillment center of about 1.4 million SF on 121 acres off I-75 in San Antonio began construction in January 2023. Pasco EDC lists 68 acres sold at Eagle Industrial Park on SR 52 for a 517,220 SF Amazon Robotics sortation center.
The new SR 52 opened February 17, 2023 ($82 million, seven miles, I-75 to US 301). FDOT began a $2.1 million package of I-75 at SR 52 ramp and turn-lane improvements on April 26, 2026, with completion estimated in late summer or early fall 2026.
What any of this means for a specific property depends on which side of the absorption curve it sits on. That's the conversation.
Common Questions About San Antonio
Two master-planned projects near the I-75 and SR 52 interchange, Double Branch and Abbey Crossings, plus a Target fulfillment center off I-75 and an Amazon Robotics site at Eagle Industrial Park on SR 52. Entitled square footage and delivered square footage are different numbers, and the gap between them is where the risk lives.
It depends on your timeline and what you need the property to produce. The infrastructure investment is real and the entitlements are in place. Absorption is the open question. An owner-user with a 15-year horizon reads this market differently than an investor who needs the space leased in 12 months.
It moved the traffic. The new four-lane divided alignment runs south of San Antonio and St. Leo, and the former route through town carries County Road 52. Property that once sat on a state road now sits on a county road. Some of that ground lost pass-through traffic and some gained a quieter, more local character. Know which side of that line a property falls on before pricing it.
Holding costs money and so does selling at the wrong point in a cycle. The question is whether your parcel benefits from what's being built or competes with it. Land that supports a use the new development creates demand for is in a different position than land competing with 400,000 square feet of entitled retail. I work through that against your actual numbers and timeline.
Neighborhood commercial along the older streets, small office and service space, industrial and warehouse at and near the interchange, and development land in between. The mix is changing as the interchange projects deliver.
Sometimes. New anchors bring traffic and rooftops, and they also bring competing space. A service business near the interchange may gain. A retailer selling what a new anchor sells may not. The honest answer requires looking at the specific property and use.
What the property is worth today, what it could support under current zoning, and who the realistic buyer is. A San Antonio property draws a different buyer pool than a comparable property in Wesley Chapel or Tampa, so pricing and marketing should reflect that.
If your situation isn't covered here, the next step is a conversation.
Three minutes on your lease, property, location, and ownership structure. You get a straight read on what's working and what isn't.
Selling commercial property Buying or leasing Investment property
Other Markets
Dade City · Zephyrhills · Wesley Chapel · Pasco County · Tampa Bay
Where this comes from
Updated October 3, 2026.